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:: Volume 5, Issue 3 (19 2011) ::
mrj 2011, 5(3): 13-24 Back to browse issues page
Systematic review article of Berlin Bedrest studies about  prolonged bedrest effects on lower limb musculoskeletal system
Rahimeh Mahmoodi1, S.Javad Mousavi 2
1- دانشکده توانبخشی دانشگاه علوم پزشکی تهران
2- دانشکده توانبخشی دانشگاه علوم پزشکی تهران , jmousavi@razi.tums.ac.ir
Abstract:   (12838 Views)

Background and aim: Many studies have been carried out about bedrest and its effects on different systems including musculoskeletal,neuromuscular,cognition and vascular systems throughout the world.The purpose of this paper is to review systematically all Berlin Bedrest Studies on musculoskeletal system.The focus of this review is  mainly Second  Berlin Bedrest Study (2nd BBRS) supported by European Space Agency(ESA).Such studies provide a chance to study the specific effects of immobilization without interference of other diseases.
Materials and Methods: A literature search was carried out using MEDLINE and ESA database to assess existing literature about the effect of bedrest on musculoskeletal system published by Berlin Bedrest Studies.It has been searched for efficacy of interventions  as high load resistive exercise and whole body vibration,as well.
Results: Fourty six articles have been found from 2000 to 2011year: 2 articles in 2000 and 2003,the other ones  between 2005 to 2011. Seventeen  articles were related to muscle and intervention on it,three ones about bone and related intervention on it,four  ones related to both bone and muscle and twenty two ones about the other systems  such as heart,vesseles,sleep and cognition.
Conclusion: According‏‏‏ to study results,bedrest has widespread effects on musculoskeletal system specially in early bedrest . These  effects remain up to 180 days  after bedrest course.Thus,high load resistive exercise and vibration should be prescribed in early stage of bedrest to reduce the detrimential effects of prolonged bedrest.

Keywords: Berlin Bedrest, Muscle Atrophy, Bone Loss, Resistive Exercise, Vibration
Full-Text [PDF 569 kb]   (1890 Downloads)    
Type of Study: Research | Subject: General
Received: 2011/05/8 | Accepted: 2011/10/27 | Published: 2013/07/13
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Mahmoodi R, Mousavi S. Systematic review article of Berlin Bedrest studies about  prolonged bedrest effects on lower limb musculoskeletal system. mrj. 2011; 5 (3) :13-24
URL: http://mrj.tums.ac.ir/article-1-61-en.html

Volume 5, Issue 3 (19 2011) Back to browse issues page
فصلنامه توانبخشی نوین Journal of Modern Rehabilitation
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